PROVEN EFFECTIVE – All Culturelle probiotics are powered by Lactobacillus rhamnosus GG (LGG), the single-strain super probiotic. LGG is the #1 most clinically studied probiotic strain. Supports your natural immune defenses DAILY IMMUNE HEALTH* – LGG works naturally with your body to help restore the natural balance of good bacteria in your digestive tract, where 70% of the immune system resides. * Balancing the bacteria in the intestines helps optimize your immune system and supports your natural defenses NO REFRIGERATION REQUIRED –Every package of Culturelle meets the highest standards for purity and potency when consumed - not just when we make it. To preserve the billions of CFU’s (colony-forming units) in your Culturelle, store it in a cool, dry place away from direct sunlight SAFE AND EFFECTIVE – Over 1, 000 scientific studies and 30 years of research have demonstrated the safety and efficacy of LGG probiotics. Culturelle is vegetarian and contains no gluten≠, milk, soy, wheat or preservatives PROBIOTIC POWER – The doctors that discovered LGG found that it is strong enough to survive stomach acids and successfully set up shop in the intestines. Culturelle Pro-Well is powered by 15 billion CFU’s of LGG During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.